Columbia Care - Dayton is a recreational retail dispensary located in Dayton, Ohio.
Address: 333 Wayne Ave, Dayton, Ohio 45403
Columbia Care - Dayton sits in the heart of Dayton, Ohio’s east side, operating in the 45403 ZIP Code and serving a community that has steadily embraced legal cannabis through both the medical program and, where licensed, adult-use sales. The store is part of a broader network of dispensaries that have helped Dayton residents access regulated products, lab-tested information, and one‑on‑one guidance as Ohio’s cannabis framework has evolved. For locals in East Dayton neighborhoods like St. Anne’s Hill and Huffman, and for commuters approaching from downtown or the suburbs, the location balances convenience, compliant access, and a familiar retail experience that feels tailored to the rhythms of the city.
Understanding where 45403 sits within Dayton makes visiting Columbia Care - Dayton straightforward. The ZIP Code covers the east-of-downtown corridor bounded by the US 35 and State Route 4 trunk lines, two high-capacity routes that define much of the area’s traffic flow. US 35 runs along the south edge of the core and bends east toward Beavercreek and Xenia, while SR 4 arcs northeast toward Riverside, Huber Heights, and Wright-Patterson Air Force Base. Within this grid, East Third Street, East Fifth Street, Keowee Street, Linden Avenue, and Springfield Street carry most of the cross‑town movement. Residential blocks mix with small businesses, light industrial spaces, and several historic districts, creating a street network that is easier to navigate than downtown’s one-way pairs and less congested than the I‑75 corridor at rush hour. If you are comparing dispensaries in Dayton, the 45403 location offers an appealing balance between proximity to downtown and quick access for drivers coming from multiple directions.
Driving to the dispensary is simplest if you’re approaching on US 35 or SR 4. From downtown or I-75, the most direct approach is to take US 35 east and exit for Keowee Street or Smithville Road, depending on your entry point to the neighborhood. Keowee runs north–south and stitches together several east‑west arterials; turning onto East Third Street or Linden Avenue from Keowee puts you within blocks of the 45403 retail cluster. Traffic along this segment of US 35 tends to be smooth outside the typical morning window of 7 to 9 a.m. and the evening outbound swell from 4 to 6 p.m. Even in those busier periods, the Keowee and Smithville exits typically move better than the I‑75 interchange because they distribute cars into a wider local grid rather than forcing long backups at a single ramp.
From the north and northeast, State Route 4 is usually the fastest route. Take SR 4 southbound and use the Stanley Avenue or Harshman Road exits to head west toward Keowee and East Third. SR 4 stays free‑flowing for most of the day because it bypasses the downtown ramps that often bottleneck. Stanley Avenue is a comparatively wide industrial corridor with multiple lanes and timed lights, so midday travel is usually quick. When Wright-Patterson has shift changes or the National Museum of the U.S. Air Force hosts large events, you can see a brief pulse of traffic along SR 4 and Harshman, but those waves dissipate by the time you reach Keowee and the 45403 streets.
South and east suburbs like Kettering, Beavercreek, Bellbrook, and Fairborn often funnel toward Columbia Care - Dayton using I‑675 and US 35. If you are coming from Beavercreek, US 35 west is the straight shot into the city. You can exit at Smithville Road and cut north to East Third, or continue to the Keowee exit for a slightly more central approach. Weekend shopping traffic near The Greene or Fairfield Commons can slow the eastern part of US 35 in the late afternoon, but that buildup rarely extends into the city grid. In winter, Montgomery County crews prioritize US 35 and SR 4 during snow and ice events, and those routes are typically cleared promptly; once you turn onto local streets, drive cautiously on bridges and shaded sections that can stay slick longer.
Once you are off the highway, the last mile is straightforward. East Third, East Fifth, and Linden are two-lane or four-lane roads with clear lane markings and reliable signage. Speed limits drop quickly from the highway to 25–35 mph, and school-zone enforcement along parts of Linden and Third is strict on weekdays. On-street parking is common across 45403, and many retailers in this corridor have small private lots as well. Street parking rules vary by block, so check posted signs before leaving your car. Rideshare drop-offs are easy because curb space is plentiful along the wider sections of East Third and Keowee, though planning your pickup on a side street can make departure faster at peak times.
Public transit is a viable choice for some visitors. Greater Dayton RTA routes moving east from Wright Stop Plaza downtown reach the 45403 neighborhoods via East Third, East Fifth, and Linden, with stops that place you within a short walk of the dispensary cluster. Transit travel times are generally consistent because these corridors avoid the densest downtown stretches. If you rely on a bus connection, building in five to ten minutes of buffer time helps account for the longer light cycles at Keowee and Third.
Local buying habits in Dayton reflect Ohio’s regulated approach to cannabis. Residents often start online by checking Columbia Care - Dayton’s menu on the company’s site or on a marketplace app and then place an order for in‑store pickup. The menu shows product categories, THC and CBD ranges, strain information, and specials, and it assigns purchase limits according to state rules. Ordering ahead tends to lock in inventory and speed up your visit. Many people browse in the morning, place a reserve, and swing by after work when traffic thins, using the evening window between 6 and 7 p.m. to avoid rush-hour backups. Walk‑ins are common as well, but product availability can change quickly on weekends, especially for popular edibles and higher‑THC flower.
At the dispensary, the check‑in process follows Ohio’s standard. You present a valid government photo ID at reception, along with a medical card if you are a registered patient. Staff verify your information, confirm that you meet the criteria for either medical or adult‑use purchasing depending on the store’s current license, and then invite you onto the sales floor. The sales interaction is conversational and consultative. If you are new to cannabis or just new to the Ohio product catalog, you can outline your goals, ask about onset times and duration, and get a guided walkthrough of options that fit your preferences. Budtenders lean on lab results printed on packaging and can help you interpret potency ranges and terpene profiles in plain language. Most shoppers in Dayton keep the visit to about fifteen minutes for a pickup order and twenty to thirty minutes for a first-time consult.
How sales work in 2025 depends on licensing. Ohio’s medical program continues to operate statewide, and adult-use sales are permitted at dispensaries that have secured an adult-use license in addition to their medical license. Whether Columbia Care - Dayton currently serves adult-use shoppers is tied to its state approval; many medical dispensaries in Ohio transitioned to dual licensing after the Division of Cannabis Control began issuing approvals in 2024. If Columbia Care - Dayton is dual‑licensed, adults 21 and older can purchase with a valid government ID, and medical patients use their state registry card to access medical tax rates and, in some cases, a broader set of products or higher purchase allotments. If the store is medical‑only at the time you visit, you will need to be a registered patient or caregiver to buy, and staff can explain the documentation you need to bring. Locals who qualified under the medical program often keep their medical card even after adult‑use sales expand because the patient tax rate is typically lower and some promotions are patient‑specific.
Products at Columbia Care - Dayton reflect Ohio’s regulated mix. You will see familiar formats like flower in a range of THC levels, pre‑rolls, vape cartridges and disposables, soft chews and chocolates, tinctures and oils, capsules, and topicals. Ohio menus identify potency clearly and include labeling that references third‑party test results. The store’s selection rotates as cultivators release new batches and as seasonal demand shifts. You can expect to see Ohio‑grown favorites from established cultivators and, at times, house labels associated with the Columbia Care portfolio when allowed by state supply chains. Seasoned shoppers in Dayton often benchmark edibles by milligrams per serving and ask about minor cannabinoids in tinctures, while flower buyers pay attention to terpene profiles, harvest dates, and moisture content because those details drive perceived freshness and flavor. The staff can help you compare strains you might recognize from other markets with the Ohio-specific phenotypes that appear on local shelves.
Payment is simple and reflects the reality of federal banking restrictions. Most dispensaries in Dayton, including Columbia Care - Dayton, accept cash and offer on‑site ATMs; many accept debit through a cashless system that posts as a rounded transaction. Traditional credit cards are rare in the cannabis space due to banking rules. Locals often bring cash for speed, and they keep an eye on daily specials and loyalty points to stretch their budget. On busy days when menus move quickly, planning a pickup and arriving within the hold window keeps your order intact and reduces time at the register.
The store’s approach to community health in 45403 feels grounded in Dayton’s larger culture of practical support. Columbia Care locations emphasize patient education and safe‑use guidance, and that same spirit shows up in Dayton through one‑on‑one consultations and printed materials that cover topics like delayed onset with edibles, safe storage at home, and avoiding impaired driving. The team commonly recognizes veterans, seniors, and caregivers with programmatic discounts, reflecting the region’s strong veteran population tied to Wright-Patterson and the National Museum of the U.S. Air Force. Around awareness months and local health fairs, the Dayton staff has been known to schedule informational days focused on cannabinoid basics and product formats, and to point people to non‑cannabis resources offered by Public Health — Dayton & Montgomery County, Five Rivers Health Centers, and area nonprofits that support mental health, housing stability, and harm reduction. Donation drives for items like winter coats or nonperishable foods are a frequent feature across the Columbia Care network and have appeared seasonally in Ohio; checking the store’s social channels is the best way to confirm current initiatives. While this is not a clinic and the staff do not provide medical advice, the emphasis on clarity and safe storage aligns with Dayton’s broader goal of connecting residents to responsible, evidence‑informed information.
Traffic patterns in the immediate area are predictable once you know the rhythm. East Third Street carries a steady stream of cars moving between the east side and downtown, with the heaviest flow in the late afternoon toward the suburbs. Keowee Street can feel busier around midday because it is a conduit for commercial traffic heading to industrial zones and a relief valve when I‑75 backs up; even then, signals are timed well enough that you move through in a few cycles. Game days at Day Air Ballpark or major shows at the Schuster Center draw people into downtown, and that can tighten the US 35 ramps for an hour or two, but once you are east of the river the streets open up quickly. If you prefer the quietest window, mornings after 10 a.m. and weekdays after 6 p.m. are typically the most relaxed times to park, pick up, and get back on your way.
Accessibility is part of the experience. Dispensaries in Ohio are required to maintain secure, compliant facilities, and that includes ADA‑accessible entrances where feasible, clear signage, and a check‑in flow that keeps the lobby organized without feeling rushed. If you need a quieter interaction or have sensory sensitivities, visiting outside peak windows helps. The Dayton team can read a product label with you, slow down to explain a dosing journal, or point you to a QR code that links to a certificate of analysis so you can do your own deep dive later. Many locals keep notes on their phone after each purchase to track which products and terpene combinations felt best, and staff are used to working from those notes to steer your next visit.
The 45403 setting also makes it easy to combine errands. The Oregon District is a short drive west with coffee, bookstores, and galleries. St. Anne’s Hill offers a walkable mix of historic homes and small businesses, and Eastwood MetroPark provides miles of trails and river views just to the northeast. It is important to remember that Ohio prohibits public consumption, so plan any activities accordingly. Keep purchases sealed in their original, child‑resistant packaging while you are out, and do not open containers in a vehicle. If you are traveling, keep in mind that crossing state lines with cannabis is illegal, even if your destination state has legal sales.
For those new to Ohio’s medical program, local residents usually start by consulting a recommending physician, either in person or via telemedicine, to determine eligibility. If approved, the physician enters the patient into the state registry, and the patient receives a digital or physical card after completing the registration. Patients then choose a dispensary and shop within the state’s purchase limits, which are shown on receipts and tracked within the program. Many patients renew annually and continue to use medical access for its tax savings and specialized promotions even after adult‑use sales are available. For caregivers, the check‑in process at the store involves showing both caregiver and patient credentials, and staff help ensure the transaction aligns with the patient’s remaining allotment. New adult‑use shoppers follow a simpler path, presenting a government ID and staying within the non‑medical possession limits at the time of purchase. In both cases, Dayton shoppers tend to plan around work hours and use online menus to streamline the visit.
When comparing cannabis companies near Columbia Care - Dayton, locals often weigh three things: drive time, menu depth, and loyalty value. The east side location ranks well on drive time for anyone living in or passing through 45403, and the menu depth reflects the scale you expect from a Columbia Care store combined with Ohio’s steady supply from established cultivators. Loyalty rewards accumulate predictably and can be applied to a wide range of items, which matters when you are building a routine. Shoppers who split their visits among multiple dispensaries in Dayton usually do so for a very specific product preference or a flash sale; otherwise, the convenience of a single, consistent stop along US 35 or SR 4 wins out.
Safety and compliance remain the throughline. Staff will remind you politely about not consuming in or around the store, and they will pack your purchase in a compliant exit bag if required. Dayton police and Montgomery County deputies enforce impaired driving laws, so plan your day with that in mind and wait to consume until you are home. If you have young people in your household, consider a lockable storage solution and keep edibles in their original packaging to avoid confusion. In summer, avoid leaving products in a hot car; heat can degrade potency and melt edibles, and vape cartridges do not tolerate extended high temperatures.
If you are navigating from outside the region, a final note on airports and interstates can help. Dayton International Airport is north of the city along I‑75, and the fastest route to 45403 is typically I‑75 south to US 35 east. Cincinnati travelers take I‑75 north and do the same, while Columbus drivers often come west on I‑70 and then drop south on I‑675 to pick up US 35 west. All of these routes flow directly to Keowee and Smithville, and each offers multiple opportunities to bypass an unexpected slowdown. In practical terms, that makes Columbia Care - Dayton a sensible stop whether you are a local or just passing through the city on business.
The bottom line for anyone researching dispensaries in Dayton is that Columbia Care - Dayton combines straightforward access in the 45403 ZIP Code with a sales process tuned to Ohio’s rules and to the way Dayton residents actually shop. The drive is easy whether you come in on US 35 or SR 4, parking and pickup are predictable, and the consultative approach helps first‑time and returning shoppers make informed choices. Layer in the store’s attention to safe‑use education and the neighborhood’s network of public health resources, and you have a dispensary that fits well within Dayton’s practical, community‑minded approach to cannabis. Whether you are comparing cannabis companies near Columbia Care - Dayton or mapping your weekly errands through East Dayton, planning your visit around the local traffic rhythm and leveraging online ordering will make the experience smooth from check‑in to checkout.
| Sunday | 09:00 AM - 05:00 PM |
|---|---|
| Monday | 09:00 AM - 05:00 PM |
| Tuesday | 09:00 AM - 05:00 PM |
| Wednesday | 09:00 AM - 05:00 PM |
| Thursday | 09:00 AM - 05:00 PM |
| Friday | 09:00 AM - 05:00 PM |
| Saturday | 09:00 AM - 05:00 PM |
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